If you are cruising down Florida's historic East Coast or planning your weekly grocery run, finding a convenient publix us1 location is likely at the top of your to-do list. Running over 500 miles from the Georgia border all the way down to the southernmost point in Key West, U.S. Highway 1 (US-1) acts as the scenic, bustling spine of the Sunshine State. Along this iconic corridor, Publix Super Markets has strategically placed some of its most popular, well-equipped, and historically significant stores.\n\nWhether you are looking for a quick "Pub Sub" for a beach picnic, need to fill a prescription at a local pharmacy, want to browse a standalone liquor store, or need to renew your vehicle registration at a DMV kiosk, this guide covers everything you need to know about finding and shopping at a publix us1 location. Let's dive into the major stores along the route, their unique services, and how you can make your next trip as seamless as possible.\n\n---\n\n## Navigating the Florida US-1 Publix Footprint: From North to South\n\nBecause U.S. Route 1 spans the entire length of Florida's Atlantic Coast, the search term "publix us1" can refer to several distinct stores depending on where you are. Below is a comprehensive, region-by-region breakdown of the most prominent Publix supermarkets situated directly on or adjacent to US-1.\n\n### Northeast Florida: St. Augustine and Jacksonville\n\nIn Northeast Florida, US-1 is a major commuter and commercial route. St. Augustine features key stores that are essential stops for both daily commuters and history-loving tourists.\n\n* St. Augustine South (7462 US-1 South, St. Augustine, FL 32086): Located on the southern stretch of US-1 in St. Johns County, this location is highly praised for its spacious aisles and expansive fresh produce section. It is a critical stop for residents in the southern suburbs of St. Augustine and those heading toward Crescent Beach.\n* St. Augustine Plaza (4255 US-1 South, St. Augustine, FL 32086): Another highly accessible store situated directly on the highway, perfect for grabbing quick deli items, bakery goods, and weekly BOGO deals.\n\n### The Treasure Coast: Sebastian, Vero Beach, and Fort Pierce\n\nAs you head further south into the Treasure Coast, US-1 runs parallel to the Indian River Lagoon. The Publix locations here are deeply integrated into their local coastal communities.\n\n* Publix at Indian River (9621 US-1, Sebastian, FL 32958): This store serves the northern portion of Sebastian. It is known for its highly rated customer service, beautifully arranged floral department, and excellent selection of local seafood.\n* Riverwalk Shopping Center (13435 US-1, Sebastian, FL 32958): Positioned further south in Sebastian, the Riverwalk Publix is highly convenient for boaters and beachgoers visiting the Sebastian Inlet. It features an adjacent Publix Liquors store and ample parking for larger vehicles or trailers.\n* Vero Beach South (1255 US Highway 1, Vero Beach, FL 32960): Officially known as Publix #0240, this location is an absolute staple for the Vero Beach community, especially during the winter season when seasonal residents arrive. It features a robust pharmacy and an extensive selection of specialty organic products.\n* Fort Pierce (2517 US-1, Fort Pierce, FL 34982): Situated in the historic Sunrise City, this Fort Pierce US-1 location is a convenient, clean, and quick spot to grab lunch or stock up on household essentials.\n\n### Southeast Florida: Fort Lauderdale and Miami\n\nIn metropolitan Southeast Florida, US-1 is often referred to as Federal Highway (in Broward County) or South Dixie Highway (in Miami-Dade County). This is where you will find some of the busiest and most historic Publix locations in the state.\n\n* Coral Ridge Mall (3200 N Federal Hwy / US-1, Fort Lauderdale, FL 33306): This site is home to Publix #70, which holds a special place in retail history. Originally opened in 1961 as a premier flagship store, it was part of Florida's very first indoor shopping mall. Today, it remains a bustling, modern supermarket that blends mid-century nostalgia with cutting-edge retail features.\n* Allapattah & US 1 Shopping Center (20711 S Dixie Hwy, Miami, FL 33189): Serving the South Miami, Cutler Bay, and Goulds neighborhoods, this massive center is situated directly on the South Dixie Highway (US-1) corridor. It is a high-volume store featuring an expansive Publix Sabor department, catering to the rich multicultural tastes of South Florida with specialized international products and hot-prepared Latin delicacies.\n\n### The Florida Keys: Overseas Highway (US-1)\n\nPerhaps the most famous stretch of US-1 is the Overseas Highway, which links the Florida Keys. If you are road-tripping down to Key West, these Publix stores are your lifelines for groceries, ice, and road-trip snacks.\n\n* Key Largo (101499 Overseas Hwy, Key Largo, FL 33037 - Mile Marker 101): The first major supermarket you encounter after leaving the mainland. It is incredibly popular for tourists stocking up on sunscreen, coolers, and fresh deli platters before heading deeper into the Keys.\n* Marathon (5407 Overseas Hwy, Marathon, FL 33050 - Mile Marker 50): Situated halfway down the island chain, the Marathon Publix is a fortress location. It features a comprehensive pharmacy, a standalone liquors store, and is the primary shopping hub for the Middle Keys.\n* Tavernier (MM 92.5, Oceanside - Upcoming): Keep an eye out for developers finalized plans for a brand-new 47,240-square-foot Publix supermarket, complete with a 2,100-square-foot liquor store and workforce housing units, designed to bring even more convenience to the Upper Keys community.\n\n---\n\n## Essential Services Offered at Publix US1 Stores\n\nWhat makes the publix us1 stores stand out isn't just their location along a major highway; it is the comprehensive suite of services they offer to make shopping a pleasure.\n\n### 1. Full-Service Publix Pharmacy\nMost US-1 Publix locations feature a dedicated, full-service pharmacy. Whether you are a local resident or a traveler passing through, you can easily transfer prescriptions using the Publix Pharmacy app. Services include:\n* Immunizations: Convenient access to flu shots, shingles vaccines, pneumonia vaccines, and more with no appointment necessary.\n* Sync Your Refills: Combine all your monthly prescriptions to be picked up on a single, convenient day.\n* Pet Medications: Publix pharmacies can fill many common veterinary prescriptions for your furry family members.\n\n### 2. Standalone Publix Liquors\nMany of the locations along the US-1 corridor—such as those in Sebastian, Vero Beach, and Marathon—feature adjacent or standalone Publix Liquors stores. These locations offer great deals on domestic and imported wines, craft beers, and a wide variety of spirits. Be sure to look out for regional wine specials and bundled deals.\n\n### 3. MV Express DMV Tag Kiosks\nOne of the most useful, yet under-utilized, services at select Florida Publix stores is the MV Express Kiosk. In partnership with local county tax collectors (such as in St. Johns County near St. Augustine), these blue-and-yellow touchscreen kiosks allow you to renew your vehicle registration and print your official license plate sticker in under two minutes while you do your grocery shopping. All you need is your renewal notice pin or your current registration card and a credit card.\n\n### 4. Instacart Delivery & Curbside Pickup\nIf you are on a tight schedule or traveling in an RV and want to avoid navigating crowded parking lots, almost all publix us1 stores offer curbside pickup and home/hotel delivery powered by Instacart. You can order online, choose a pickup window, and a friendly Publix associate will load the groceries directly into your trunk.\n\n---\n\n## Store Directory Table: Quick Reference for Key US-1 Locations\n\nTo help you find the exact store you need, here is a quick-reference directory of the most highly searched Publix stores on U.S. 1 in Florida:\n\n| Store Name / Plaza | Address | Pharmacy? | Liquor Store? | Unique Features |\n| :--- | :--- | :--- | :--- | :--- |\n| St. Augustine South | 7462 US-1 S, St. Augustine, FL 32086 | Yes | Yes | DMV Tag Kiosk, EV Charging |\n| Riverwalk Center | 13435 US-1, Sebastian, FL 32958 | Yes | Yes | Coastal location, Great deli |\n| Vero Beach South | 1255 US Highway 1, Vero Beach, FL 32960 | Yes | No | Huge organic selection (GreenWise) |\n| Coral Ridge Mall | 3200 N Federal Hwy, Ft. Lauderdale, FL 33306 | Yes | Yes | Historic Store #70, Indoor Mall access |\n| Allapattah & US 1 | 20711 S Dixie Hwy, Miami, FL 33189 | Yes | Yes | Publix Sabor, Hot Hispanic Foods |\n| Key Largo | 101499 Overseas Hwy, Key Largo, FL 33037 | Yes | Yes | Mile Marker 101, Road-trip central |\n| Marathon | 5407 Overseas Hwy, Marathon, FL 33050 | Yes | Yes | Mile Marker 50, Middle Keys Hub |\n\n---\n\n## How to Plan the Perfect "Pub Sub" Pit Stop Along US-1\n\nNo trip down Florida’s East Coast on US-1 is truly complete without stopping for a legendary Publix Deli Sub, affectionately known as a "Pub Sub." Whether you are heading to the beach in Vero Beach or driving down to Key West, planning your lunch stop ahead of time can save you hours of waiting in line.\n\n### Step 1: Order Ahead via the Publix App\nDuring peak lunch (11:30 AM to 1:30 PM) and dinner hours, the deli line at any publix us1 location can get incredibly long. Download the Publix App or go online to customize your sub. You can choose your bread (white, wheat, or Italian 5-grain), cheese, toppings, and sauces, and set a precise pickup time.\n\n### Step 2: Choose the Ultimate Sub\nWhile the classic Tavern Ham or Turkey Sub is always a safe bet, the undisputed king of the deli is the Publix Chicken Tender Sub. You can even ask to have your tenders tossed in Buffalo sauce or topped with melted cheddar and bacon (the "chicken parm" style). If you are looking for something smoky and hearty, look out for their seasonal smoked brisket subs.\n\n### Step 3: Grab Your Sides and Head to the Beach\nOnce you grab your sub from the designated online pickup shelf, head over to the chip aisle, grab a sweet tea (Publix brand sweet tea is legendary), and drive to the nearest coastal park. Along US-1, you are never more than a few minutes away from a gorgeous public beach or riverfront park.\n\n---\n\n## Insider Shopping Tips: How to Save at Publix on US-1\n\nPublix is renowned for its clean stores and premier customer service, but it can sometimes be pricier than discount grocers. Use these expert shopping hacks to keep your grocery bill low:\n\n* Master the BOGOs: Publix’s "Buy One, Get One Free" deals change every Thursday (or Wednesday in some regions). These sales cover everything from cereal and ice cream to high-quality meats and laundry detergent. Best of all, in most Florida stores, you don’t actually have to buy two items to get the discount; a single item will ring up at half-price.\n* Join Club Publix: This is Publix’s free digital loyalty program. By signing up, you get access to exclusive digital coupons, sneak peeks of the weekly ad, personalized product recommendations, and even a free treat on your birthday.\n* Look for Extra Savings Flyers: When you walk through the front doors, look for the green and purple "Extra Savings" flyers. These contain store coupons that can often be stacked with manufacturer coupons for massive savings.\n* Buy Store Brands: The Publix store brand products (including their organic GreenWise line) are exceptionally high quality, often rivaling or beating national brands at a fraction of the cost.\n\n---\n\n## Frequently Asked Questions (FAQ)\n\n### What are the typical operating hours for a Publix US1 store?\nMost Publix stores along the US-1 corridor are open daily from 7:00 AM to 10:00 PM. However, hours can occasionally vary by location or during major holidays (such as Thanksgiving and Christmas, when all Publix locations are closed). It is always best to check the official Publix store locator for real-time hours.\n\n### Can I renew my vehicle registration at any Publix on US-1?\nNo, vehicle registration renewal kiosks (MV Express Kiosks) are only available at select locations. For example, you can find them at the St. Augustine South Publix on US-1 in St. Johns County. You must check with your local county's Tax Collector website to see a list of active retail kiosk locations.\n\n### Does Publix on US-1 offer curbside pickup?\nYes, almost all Publix stores along US-1 offer curbside pickup and delivery services managed through Instacart. Look for the designated parking spaces marked with signs when you arrive to have your groceries brought directly to your vehicle.\n\n### Are Publix Liquors stores located inside the main grocery store?\nNo, Florida state law requires spirit sales to be physically separated from grocery sales. Therefore, Publix Liquors stores are always located in a separate storefront immediately adjacent to the main supermarket or in the same shopping plaza.\n\n---\n\n## Conclusion\n\nWhether you are a local resident running your weekly errands or a traveler exploring the beautiful Florida coastline, the many publix us1 locations are ready to make your shopping experience a pleasure. From the historical flagship vibe of Fort Lauderdale's Coral Ridge store to the tropical, road-trip-essential stops throughout the Florida Keys, these supermarkets offer unmatched convenience, fresh food, and premium services. Next time you travel along U.S. 1, use this guide to plan your stops, grab a world-famous Pub Sub, utilize convenient services like DMV kiosks, and save money using the weekly BOGO specials. Happy shopping!